International Journal for Numerical Methods in Biomedical Engineering (2018)
Finsberg Henrik, Xi Ce, Tan Ju Le, Zhong Liang, Genet Martin, Sundnes Joakim, Lee Lik Chuan, and Wall Samuel
By Faucher Benjamin, Assab Rania, Roux Jonathan, Levy-Bruhl Daniel, Tran-Kiem Cécile, Cauchemez Simon, Zanetti Laura, Colizza Vittoria, Boëlle Pierre-Yves, and Poletto Chiara
Working Paper (2021)
As vaccination against COVID-19 stalls in some countries, increased accessibility and more agile administering of vaccines is necessary to keep the epidemic under control. Here we study the impact of reactive vaccination targeting schools and workplaces where cases have been detected, with an agent-based model accounting for COVID-19 natural history, vaccine characteristics, individuals’ demography and behavior and social distancing. We study epidemic scenarios ranging from sustained spread to flare-up of cases, and we consider reactive vaccination alone and in combination with mass vaccination. With the same number of doses, reactive vaccination reduces cases more than non targeted approaches, but may lead to large peak demand in vaccines in case of sustained spread. In case of flare-ups, quick implementation of reactive vaccination supported by enhanced test / trace/ isolate practices would limit further spread. These results provide key information to plan vaccination in the months to come.
Faucher B., Assab R., Roux J., Levy-Bruhl D., Tran-Kiem C., Cauchemez S., Zanetti L., Colizza V., Boëlle P., and Poletto C. (2021) Reactive vaccination of workplaces and schools against COVID-19. Working Paper.